Soyuz TMA-21 launched from Baikonur Site 1/5 on April 4, 2011 UTC, one week before the 50th anniversary of Yuri Gagarin's first human spaceflight. The spacecraft, nicknamed Gagarin, carried Roscosmos commander Aleksandr Samokutyayev, Roscosmos flight engineer Andrei Borisenko, and NASA flight engineer Ronald Garan to the International Space Station. After docking with the station's Poisk module on April 6, the crew served through Expeditions 27 and 28, supporting station research, maintenance, visiting vehicles, and final Shuttle-era operations. The same crew returned to Earth aboard Soyuz TMA-21 on September 16, 2011, landing southeast of Dzhezkazgan, Kazakhstan.