SpaceX Crew-10 was NASA's tenth operational Commercial Crew rotation to the International Space Station. Anne McClain commanded the flight, Nichole Ayers served as pilot, and Takuya Onishi and Kirill Peskov flew as mission specialists. The crew launched from Launch Complex 39A on March 14, 2025, docked with the station, and supported Expeditions 72 and 73. During the mission, the crew carried out station research, maintenance, technology demonstrations, and handover work with arriving and departing crews. Crew-10 undocked in August and splashed down off California on August 9, 2025, ending a 147-day mission for Ayers and Peskov and the second spaceflights for McClain and Onishi.