Soyuz MS-21 was a Roscosmos Soyuz MS spacecraft, MS No. 750, launched from Baikonur Site 31/6 on March 18, 2022 UTC. It carried commander Oleg Artemyev and flight engineers Denis Matveyev and Sergei Korsakov to the International Space Station for Expedition 66 and Expedition 67. The same three cosmonauts returned aboard the spacecraft on September 29, 2022, landing in Kazakhstan after about 195 days in space.